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OUR PIPELINE

Defined by need.
Developed through evidence.

A focused portfolio of engineered biological candidates, with each program evaluated against its own scientific, manufacturing and clinical requirements.

DEVELOPMENT SNAPSHOT · SEPTEMBER 2026
Original featured pipeline illustration

Featured programs

3 programs shown

PROGRAM / MODALITYRESEARCH INDICATIONDEVELOPMENT FOCUS
Musculoskeletal

FGF18–MSC

mRNA-engineered mesenchymal stromal cells

RESEARCH INDICATIONKnee osteoarthritis
Preclinical development

Cartilage repair & joint function

Tissue repair

Decorin–EV

Engineered extracellular vesicles

RESEARCH INDICATIONIdiopathic pulmonary fibrosis
Product design & preclinical evaluation

Pulmonary delivery & fibrosis biology

Vascular

VEGFA–MSC

mRNA-engineered mesenchymal stromal cells

RESEARCH INDICATIONSevere lower-limb ischemia
Translational development

Perfusion & tissue repair

These descriptions summarize current research directions rather than regulatory phase designations. Product-specific filings, study authorizations and enrollment are separate milestones.

A BROADER RESEARCH BASE

Building the next
generation of candidates.

Our September 2026 portfolio planning identifies four priority translational projects and eight research-stage projects. These planning groups are not counts of approved clinical studies.

CELL THERAPY

Immune-cell programs

Autologous, allogeneic and engineered NK-cell concepts are being explored in defined oncology and hematology settings.

PAYLOAD RESEARCH

40+ candidate factors

A research base across five therapeutic areas supports target evaluation, expression studies and product selection.

PORTFOLIO DEVELOPMENT

Evidence at each step

Candidate selection depends on mechanism, reproducibility, manufacturability and a credible development pathway.

DEVELOPMENT PRINCIPLES

The right evidence.
For each next step.

What does “investigational” mean?

The candidate remains in research or development. The descriptions on this website do not establish safety, efficacy or authorization for commercial use.

How do we describe clinical readiness?

Product definition, nonclinical evidence, manufacturing readiness, institutional review, study filing and patient enrollment are assessed separately. Completion of one does not imply completion of the others.

How can partners evaluate a program?

Contact our business development team to discuss a program-specific review. The scope of information sharing, available evidence and cooperation terms can be agreed for each opportunity.

Original clinical evidence illustration
Original clinical evidence cycle diagram
Original lower-limb ischemia, pulmonary fibrosis and validation illustration
PARTNER WITH LOTUSLAKE

A shared ambition.
A specific opportunity.

Bring a clinical challenge, a scientific discovery or a development ambition. Let’s explore what we can build together.

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